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New tendencies in vision of asthma. Neurogenic aspects of disease

Bronchial asthma and other neurogenic diseases:
migraine, trigeminal neuralgia and epilepsy

Similarities with Migraine, Epilepsy and Trigeminal Neuralgia

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Antiepileptic drugs against asthma in ERS Congresses: Glasgow, 2004,
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[ Asthma as
Paroxysmal
Condition ]

Asthma is neurogenic inflamamtory disease with paroxysmal clinical picture.

Migraine and trigeminal neuralgia are neurogenic inflammatory diseases with paroxysmal clinical picture.

Antiepileptic drugs are effective in pharmacotherapy of migraine, trigeminal neuralgia, epilepsy and bronchial asthma.

Asthma, epilepsy, migraine and trigeminal neuralgia have some similarities in mechanisms.

Similarities in Asthma, Migraine, Trigeminal Neuralgia and Epilepsy

Bronchial Asthma	Migraine	Trigeminal Neuralgia (TGN)	Epilepsy
Asthma as Neurogenic Inflammatory Disease (Joos et al, 2003)	Migraine as Neurogenic Inflammatory Disease (Williamson, Hargreaves, 2001)	TGN as Neurogenic Inflammatory Disease (Strittmatter et al, 1996)	Inflammation and Epilepsy (Vezzani, Granata, 2005)
Asthma as Paroxysmal Disease (Canadian Asthma Consensus Guideline, 1999)	Migraine as Paroxysmal Disease (Diener, 2003)	TGN as Paroxysmal Disease (Juniper, Glynn, 1999)	Epilepsy as Paroxysmal Disease (Gibbs, Gibbs, Lennox, 2002)
Similar Provocative Effects of Some Substances
Cytokines and Asthma (Simon, 2006)	Cytokines and Migraine (Reuter et al, 2001)	------	Cytokines and Epilepsy (Vezzani et al., 2004)
Kynurenines and Asthma (Ivanova et al, 1988)	Kynurenines and Migraine (Velling et al, 2003)	Kynurenines and TGN (Knyihar-Csillik 2004)	Kynurenines and Epilepsy (Lapin, 1983)
Substance P and Asthma (Tomaki et al, 1995)	Substance P and Migraine (De Vane, 2001)	Substance P and TGN (De Vane, 2001)	Substance P and Epilepsy (Liu et al, 1999)
Leukotrienes and Asthma (Dahlen, 2006)	Leukotrienes and Migraine (Sheftell et al, 2000)	------	Leukotrienes and Epilepsy (Phillis et al, 2006)
Prostaglandins and Asthma (Nishimura et al, 2001)	Prostaglandins and Migraine (Bic et al, 1998)	------	Prostaglandins and Epilepsy (Bhaduri et al, 1995)
Glutamate and Asthma (Allen et al, 1987)	Glutamate and Migraine (Peres et al, 2004)	------	Glutamate and Epilepsy (Meldrum, 1994)
Similar Protective Effects of Some Substances
GABA and Asthma (Dicpinigaitis, 1999)	GABA and Migraine (Spina, Perugi, 2004)	GABA and TGN (Spina, Perugi, 2004)	GABA and Epilepsy (Karceski et al, 2005)
Taurine and Asthma (Cortijo et al, 2001)	Taurine and Migraine (Martinez, 1993)	------	Taurine and Epilepsy (Birdsall, 1998)
Glycine and Asthma (Fogarty et al, 2004)	------	Glycine and TGN (Megdiatov et al, 1991)	Glycine and Epilepsy (Liu et al, 1999)
Similarities in Therapy
Therapy of asthma by anticonvulsants (Lomia et al, 2006)	Therapy of migraine by anticonvulsants (Spina, Perugi, 2004)	Therapy of TGN by anticonvulsants (Spina, Perugi, 2004)	Therapy of epilepsy by anticonvulsants (Karceski et al, 2005)

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Send mail towith questions or comments about this web site. Copyright © 2005 Merab Lomia Last modified: March 26, 2006

Send mail towith questions or comments about this web site.
Copyright © 2005 Merab Lomia
Last modified: March 26, 2006