New tendencies in vision of asthma. Neurogenic aspects of disease
Bronchial asthma and other neurogenic diseases:
migraine, trigeminal neuralgia and epilepsy
Similarities with Migraine, Epilepsy and Trigeminal Neuralgia
[ Carbamazepine in Asthma Therapy ] [ Valproates in Asthma Therapy ] [ Author ]
[ Scientific Background ] [ For Patients ] [ Articles, Congresses and Patent ]
Antiepileptic drugs against asthma in ERS Congresses: Glasgow, 2004,
Copenhagen, 2005, [ Presentation ] and Munich, 2006
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[ Neuroasthma Group ]
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[ Asthma as



Asthma is neurogenic inflamamtory disease with paroxysmal clinical picture.

Migraine and trigeminal neuralgia are neurogenic inflammatory diseases with paroxysmal clinical picture.

Antiepileptic drugs are effective in pharmacotherapy of migraine, trigeminal neuralgia, epilepsy and bronchial asthma.

Asthma, epilepsy, migraine and trigeminal neuralgia have some similarities in mechanisms.

Similarities in Asthma, Migraine, Trigeminal Neuralgia and Epilepsy

Bronchial Asthma
Trigeminal Neuralgia (TGN)
Asthma as Neurogenic
Inflammatory Disease
(Joos et al, 2003)
Migraine as Neurogenic
Inflammatory Disease
(Williamson, Hargreaves, 2001)
TGN as Neurogenic
Inflammatory Disease
(Strittmatter et al, 1996)
Inflammation and
Epilepsy (Vezzani,
Granata, 2005)
Asthma as Paroxysmal
Disease (Canadian
Asthma Consensus
Guideline, 1999)
Migraine as Paroxysmal
Disease (Diener, 2003)
TGN as Paroxysmal
Disease (Juniper,
Glynn, 1999)
Epilepsy as Paroxysmal
Disease (Gibbs, Gibbs,
Lennox, 2002)
Similar Provocative Effects of Some Substances
Cytokines and Asthma
(Simon, 2006)
Cytokines and Migraine
(Reuter et al, 2001)
Cytokines and Epilepsy
(Vezzani et al., 2004)
Kynurenines and Asthma
(Ivanova et al, 1988)
Kynurenines and Migraine
(Velling et al, 2003)
Kynurenines and TGN
(Knyihar-Csillik 2004)
Kynurenines and Epilepsy
(Lapin, 1983)
Substance P and Asthma
(Tomaki et al, 1995)
Substance P and Migraine
(De Vane, 2001)
Substance P and TGN
(De Vane, 2001)
Substance P and Epilepsy
(Liu et al, 1999)
Leukotrienes and Asthma
(Dahlen, 2006)
Leukotrienes and Migraine
(Sheftell et al, 2000)
Leukotrienes and Epilepsy
(Phillis et al, 2006)
Prostaglandins and
Asthma (Nishimura et al,
Prostaglandins and
Migraine (Bic et al, 1998)
Prostaglandins and
Epilepsy (Bhaduri et
al, 1995)
Glutamate and Asthma
(Allen et al, 1987)
Glutamate and Migraine
(Peres et al, 2004)
Glutamate and Epilepsy
(Meldrum, 1994)
Similar Protective Effects of Some Substances
GABA and Asthma
(Dicpinigaitis, 1999)
GABA and Migraine
(Spina, Perugi, 2004)
(Spina, Perugi, 2004)
GABA and Epilepsy
(Karceski et al, 2005)
Taurine and Asthma
(Cortijo et al, 2001)
Taurine and Migraine
(Martinez, 1993)
Taurine and Epilepsy
(Birdsall, 1998)
Glycine and Asthma
(Fogarty et al, 2004)
                   ------ Glycine and TGN
(Megdiatov et al, 1991)
Glycine and Epilepsy
(Liu et al, 1999)
                                                                         Similarities in Therapy
Therapy of asthma
by anticonvulsants
(Lomia et al, 2006)
Therapy of migraine
by anticonvulsants
(Spina, Perugi, 2004)
Therapy of TGN
by anticonvulsants
(Spina, Perugi, 2004)
Therapy of epilepsy
by anticonvulsants
(Karceski et al, 2005)



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Last modified: March 26, 2006


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